SYNTHESIS OF ISOXAZOLO[4,5-<i>b</i>]PYRIDINE DERIVATIVES

Authors

  • Vladislav V. Nikol'skiy N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991
  • Alexey M. Starosotnikov N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991

DOI:

https://doi.org/10.1007/7376

Keywords:

isoxazolo[4, 5-b]pyridines, nitrogen heterocycles

Abstract

The most recent approaches toward isoxazolo[4,5-b]pyridine derivatives are discussed. The microreview covers the latest selected examples (2012–2022) on the synthesis of isoxazolo[4,5-b]pyridines via two main approaches: annulation of a pyridine ring to 4-aminoisoxazoles and isoxazole ring closure in functionalized pyridine derivatives. In addition, some special cases of the isoxazolo[4,5-b]pyridine system formation will be mentioned.

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Published

2023-05-31

Issue

Vol. 59 No. 4/5 (2023)

Section

Heterocycles in Focus