4-HYDROXY-2-QUINOLONES. 110. BROMINATION OF 1-R-4-HYDROXY-2-OXO-1,2-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ANILIDES

Authors

  • И. В. Украинец National Pharmaceutical University, Kharkiv 61002
  • А. А. Ткач National Pharmaceutical University, Kharkiv 61002
  • Л. В. Сидоренко National Pharmaceutical University, Kharkiv 61002
  • О. В. Горохова National Pharmaceutical University, Kharkiv 61002

DOI:

https://doi.org/10.1007/7773

Keywords:

4-hydroxy-2-oxo-1, 2-dihydroquinoline-3-carboxylic acid amides, bromination, X-ray analysis, antitubercular activity

Abstract

1-R-4-Hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid anilides have been prepared. It has been shown experimentally that these compounds are brominated by molecular bromine in glacial acetic acid at position 4 of the anilide fragment. The antitubercular properties of the  compounds synthesized are discussed.

How to Cite
Ukrainets, I. V.; Tkach, A. A.; Sidorenko,L. V.; Gorokhova, O. V.  Chem. Heterocycl. Compd. 2006, 42, 1301. [Khim. Geterotsikl. Soedin. 2006, 1508.]

For this article in the English edition see DOI 10.1007/s10593-006-0239-3


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Published

2023-05-03

Issue

No. 10 (2006)

Section

Original Papers