HETEROCYCLIC ANALOGS OF 5,12-NAPHTHACENEQUINONE. 4. SYNTHESIS OF 4,11-DIMETHOXYANTHRA[2,3-<i>d</i>]ISOXAZOLE-5,10-DIONE

Authors

  • А. Е. Щекотихин G. F. Gauze Institute of New Antibiotics, Russian Academy of Medical Science, 119021 Moscow
  • Ю. H. Лузиков G. F. Gauze Institute of New Antibiotics, Russian Academy of Medical Science, 119021 Moscow
  • В. Н. Буянов D. I. Mendeleev University of Chemical Technology of Russian, 125190 Moscow
  • M. Н. Преображенская G. F. Gauze Institute of New Antibiotics, Russian Academy of Medical Science, 119021 Moscow

DOI:

https://doi.org/10.1007/7829

Keywords:

acetone oxime, 3-chloro-1, 4-dimethoxy-9, 10-anthracenedione-2-carbaldehyde, 4, 11-dimethoxyanthra[2, 3-d]isoxazole-5, 10-dione, nucleophilic aromatic substitution, transoximation

Abstract

A preparative synthetic method has been developed for 3-chloro-2-formyl-1,4-dimethoxyanthraquinone starting from available 2-methylquinizarine. The condensation of the  α-chloroaldehyde obtained with acetone oxime gives 4,11-dimethoxyanthra[2,3-d]isoxazole-5,10-dione.

How to Cite
Shchekotikhin, A. E.; Luzikov, Yu. N.; Buyanov, V. N.;  Preobrazhenskaya, M. N.  Chem. Heterocycl. Compd. 2006, 42, 1236. [Khim. Geterotsikl. Soedin. 2006, 1421.]

For this article in the English edition see DOI 10.1007/s10593-006-0232-x


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Published

2023-05-24

Issue

No. 9 (2006)

Section

Original Papers