4-HYDROXY-2-QUINOLONES. 95. SYNTHESIS, STRUCTURE, AND ANTITUBERCULAR PROPERTIES OF HETARYLAMIDES OF 4-HYDROXY-2-OXO-1,2,5,6,7,8-HEXAHYDROQUINOLINE-3-CARBOXYLIC ACID

Authors

  • И. В. Украинец National Pharmaceutical University, Kharkov 61002
  • Е. В. Колесник National Pharmaceutical University, Kharkov 61002
  • Л. В. Сидоренко National Pharmaceutical University, Kharkov 61002
  • О. В. Горохова National Pharmaceutical University, Kharkov 61002
  • А. В. Туров Kiev Taras Shevchenko National University, Kiev 01033

DOI:

https://doi.org/10.1007/7953

Keywords:

amides, 4-hydroxy-2-oxoquinoline-3-carboxylic acids, antitubercular activity, X-ray structural analysis, thermolysis

Abstract

The optimal conditions for obtaining hetarylamides of 4-hydroxy-2-oxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid are suggested on the basis of derivatographic investigations. The 1H NMR spectra of the synthesized compounds, their spatial structure, and also the results of a study of their antitubercular properties are discussed.

How to Cite
Ukrainets, I. V.; Kolesnik, E. V.; Sidorenko, L. V.; Gorokhova, O. V.; Turov, A. V.  Chem. Heterocycl. Compd. 2006, 42, 765. [Khim. Geterotsikl. Soedin. 2006, 874.]

For this article in the English edition, see DOI 10.1007/s10593-006-0159-2


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Published

2023-08-14

Issue

No. 6 (2006)

Section

Original Papers