SYNTHESIS OF 2-UNSUBSTITUTED 1-ARYLIMIDAZOLES

Authors

  • В. С. Митянов D. Mendeleev University of Chemical Technology of Russia
  • В. П. Перевалов D. Mendeleev University of Chemical Technology of Russia
  • И. И. Ткач D. Mendeleev University of Chemical Technology of Russia

DOI:

https://doi.org/10.1007/853

Keywords:

1-arylimidazoles, boron trifluoride, imidazole N-oxides, heterocyclization, N-oxide reduction

Abstract

A method has been developed for the synthesis of 1-arylimidazoles lacking a substituent at position 2, featuring the preparation of 1-arylimidazole N-oxides stabilized as boron trifluoride derivatives, with subsequent reduction to the desired imidazoles. This method permits broad variation of the substituents in the aryl part of these molecules.

Authors: V. S. Mityanov, V. P. Perevalov, and I. I. Tkach

English Translation in Chemistry of Heterocyclic Compounds, 2013, 48 (12), pp 1793-1800

http://link.springer.com/article/10.1007/s10593-013-1210-8

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Published

2013-08-20

Issue

No. 12 (2012)

Section

Original Papers