4-OXO-3,4-DIHYDROQUINAZOLINYL- AND BENZIMIDAZOLYLACETONITRILES IN ANNELATION REACTIONS OF A HALOQUINOLINE RING

Authors

  • O. V. Khilya Taras Shevchenko National University, Kiev 01033
  • T. A. Volovnenko Taras Shevchenko National University, Kiev 01033
  • A. V. Turov Taras Shevchenko National University, Kiev 01033
  • Yu. M. Volovenko Taras Shevchenko National University, Kiev 01033

Keywords:

benzimidazolylacetonitrile, 2-(1H-benzo[d]imidazol-2-yl)-3-(2,6-dihalophenyl)acrylonitriles, 4-halobenzo[4,5]imidazo[1,2-a]quinoline-6-carbonitriles, 4-halo-12-oxo-12H-quino[2,1-b]-quinazoline-6-carbonitriles, 3-(2,6-dihalophenyl)-2-(4-oxo-3,4-dihydro-2-quinazolinyl)acrylonitriles, 4-oxo-3,4-dihydroquinazolinylacetonitrile

Abstract

The interaction of 4-oxo-3,4-dihydroquinazolinyl- and benzimidazolyl-acetonitriles with 2,6-dihalo-benzaldehydes leads to 3-(2,6-dihalophenyl)-2-(4-oxo-3,4-dihydro-2-quinazolinyl)acrylonitriles and 2-(1H-benzo[d]imidazol-2-yl)-3-(2,6-dihalophenyl)acrylonitriles respectively. As a result of intramolecular cyclization of these nitriles 4-halo-12-oxo-12H-quino[2,1-b]quinazoline-6-carbonitriles and 4-halobenzo[4,5]-imidazo[1,2-a]quinoline-6-carbonitriles respectively are formed.

How to Cite
Khilya, O. V.; Volovnenko, T. A.; Turov, A. V.; Volovenko, Yu. M. Chem. Heterocycl. Compd. 2004, 40, 1063. [Khim. Geterotsikl. Soedin. 2004, 1226.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000046698.75658.49

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Published

2004-08-25

Issue

No. 8 (2004)

Section

Original Papers