MODERN APPROACHES TO THE SYNTHESIS OF PHENAZINE DERIVATIVES

Authors

  • Vadim V. Nadtochiy Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002
  • Igor L. Nikonov Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 Sofyi Kovalevskoi St., Yekaterinburg 620219. Ural State Forest Engineering University, 37 Sibirskiy trakt St., Yekaterinburg 620100
  • Grigory V. Zyryanov Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 Sofyi Kovalevskoi St., Yekaterinburg 620219

Abstract

Phenazine and its derivatives are of interest in medicinal chemistry and modern pharmacology as promising drugs for antibiotic therapy. This is of special importance in light of the observed antibiotic resistance in pathogenic microorganisms. This review presents the principal methods for the synthesis of derivatives of phenazine, including its biologically active tandem conjugates published over the past 10 years.

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Published

2024-08-01

Issue

Vol. 60 No. 5/6 (2024)

Section

Heterocycles in Focus