SYNTHESIS OF 2-SUBSTITUTED 7-METHYL-6-(NITROIMIDAZOLYL)THIOPURINES

Authors

  • E. B. Александрова Zaporozhe State University of Medicine, Zaporozhe 330074
  • П. M. Кочергин Center for The Chemistry of Medicinal Substances, All-Russia Scientific Research Institute for Pharmaceutical Chemistry, Moscow 119815
  • Л. B. Персанова State Institute for Blood Replacement and Medicinal Preparations, Moscow 109044
  • В. С. Корсунский Center for The Chemistry of Medicinal Substances, All-Russia Scientific Research Institute for Pharmaceutical Chemistry, Moscow 119815
  • В. С. Шлихунова Center for The Chemistry of Medicinal Substances, All-Russia Scientific Research Institute for Pharmaceutical Chemistry, Moscow 119815

Keywords:

nitrohaloimidazoles, nitroimidazolylthiopurines, nitromercaptoimidazoles, thiopurines, chloropurines

Abstract

2-Substituted 7-methyl-6-(nitroimidazolyl)thiopurines have been synthesized by the reaction of 2‑chloro(phenylamino, cycloalkylamino)-7-methyl-6-thiopurines with 5(4)-halo-4(5)-nitroimidazoles and the reaction of 2,6-dichloro-(6-chloro-2-dimethylamino)-7-methylpurines with sodium or ammonium salts of 5(4)-mercapto-4(5)-nitroimidazoles.

How to Cite
Aleksandrova, E. V.; Kochergin, P. M.; Persanova, L. V.; Korsunskii, V. S.; Shlikhunova, V. S. Chem. Heterocycl. Compd. 2001, 37, 490. [Khim. Geterotsikl. Soedin. 2001, 538.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1017660106676

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Published

2001-04-25

Issue

No. 4 (2001)

Section

Original Papers