LINEAR ENCODING OF FUNCTIONAL GROUPS IN THE SYNTHESIS OF HETEROCYCLIC COMPOUNDS: CYCLOADDITION OF ENYNE AND ALKYNE UNITS

Авторы

  • V. P. Ananikov N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/1281

Ключевые слова:

alkyne, cyclic allene, enyne, cycloaddition, cycloaromatization, selectivity

Аннотация

A family of novel [4+2]-cycloaddition reactions is discussed to carry out efficient preparation of poly-substituted heterocyclic compounds in a single-step starting with linear precursors. High selectivity of the intramolecular transformation and pre-defined position of substituents in the product were governed by linear encoding in the structure of starting reagents. The designed reactions utilized green chemistry potential of cycloaddition approach and provided a convenient synthetic route to cyclopentapyridines, indoles, isoindoles, indolizines, isophosphindoles, benzofurans, benzothiophenes, benzoselenophenes (and corresponding dihydro derivatives).

Also published in Chemistry of Heterocyclic Compounds, 2012, 48 (1), pp 2-6

http://link.springer.com/article/10.1007/s10593-012-0959-5

Опубликован

2013-12-04

Выпуск

Раздел

Обзорные статьи