AN ENVIRONMENTALLY BENIGN AND SOLVENT-FREE SYNTHESIS OF 3-ARYL[1,2,4]TRIAZOLO[4,3-a]PYRIDINES AND 1-ARYL-5-METHYL[1,2,4]TRIAZOLO[4,3-a]QUINOLINES USING PHENYLIODINE BIS(TRIFLUOROACETATE) OR IODOBENZENE DIACETATE

P. Kumar

doi:10.1007/1369

AN ENVIRONMENTALLY BENIGN AND SOLVENT-FREE SYNTHESIS OF 3-ARYL[1,2,4]TRIAZOLO[4,3-a]PYRIDINES AND 1-ARYL-5-METHYL[1,2,4]TRIAZOLO[4,3-a]QUINOLINES USING PHENYLIODINE BIS(TRIFLUOROACETATE) OR IODOBENZENE DIACETATE

Авторы

P. Kumar Department of Chemistry, Kurukshetra University

DOI:

https://doi.org/10.1007/1369

Ключевые слова:

bridgehead triazoles, hydrazones, iodobenzene diacetate, phenyliodine bis(trifluoroacetate), grinding, oxidative cyclization, solvent-free reactions

Аннотация

A simple, solvent-free and effective method for oxidative cyclization of 2-pyridyl and 2-quinolylhydrazones with phenyliodine bis(trifluoroacetate) and iodobenzene diacetate to corresponding 3-aryl-[1,2,4]triazolo[4,3-a]pyridines and 1-aryl-[1,2,4]triazolo[4,3-a]quinolines is described. All reactions were characterized by short reaction times and high yields at room temperature. All reactions were carried out just by grinding the reaction components.

Also published in Chemistry of Heterocyclic Compounds, 2011, 47 (10), pp 1237-1243

http://link.springer.com/article/10.1007/s10593-012-0899-0