SYNTHESIS OF INDAZOLOQUINAZOLINE SYSTEM

Авторы

  • Selvaraj Mohana Roopan Department of Chemistry, School of Advanced Sciences, VIT University, Vellore 632014, Tamilnadu
  • Jeyakannu Palaniraja Department of Chemistry, School of Advanced Sciences, VIT University, Vellore 632014, Tamilnadu

DOI:

https://doi.org/10.1007/2899

Ключевые слова:

indazolo[2, 3-a]quinazolines, 3-c]quinazolines, indazolo[3, 2-b]quinazolines

Аннотация

Indazoloquinazolines are a class of heterocyclic compounds consisting of fused indazole and quinazoline fragments that can be connected with nitrogen atom as a fusion point. The tetracyclic scaffolds built that way include indazolo[2,3-c]quinazolines, indazolo[2,3-a]quinazolines, and indazolo[3,2-b]quinazolines. The natural occurrence of this compound class is rare, however, the indazolo-fused quinazolines possess a wide range of biological activities. Among those, indazolo[2,3-a]quinazolines have shown high antibacterial activity. The synthetic routes towards indazoloquinazolines can be categorised into several groups: 1) metal-catalyzed and metal-free intramolecular cyclizations; 2) metal-catalyzed and metal-free intermolecular reactions; 3) reductive intramolecular cyclization; 4) multicomponent assembly reactions.

How to Cite
Roopan, S. M.; Palaniraja, J. Chem. Heterocycl. Compd. 2016, 52, 93. [Khim. Geterotsikl. Soedin. 2016, 52, 93.]

For this article in the English edition see DOI 10.1007/s10593-016-1838-2

Биография автора

Selvaraj Mohana Roopan, Department of Chemistry, School of Advanced Sciences, VIT University, Vellore 632014, Tamilnadu

Organic Chemistry Division, SAS, VIT University, Vellore 632014.

mohanaroopan.s@vit.ac.in

Загрузки

Опубликован

2016-03-14

Выпуск

Том 52 № 2 (2016)

Раздел

Гетероциклы в фокусе