SYNTHESIS OF ENANTIOMERICALLY ENRICHED 4-ARYL-3,4-DIHYDROCOUMARINS

Авторы

  • Zigmars Leitis Latvian Institute of Organic Synthesis

DOI:

https://doi.org/10.1007/3148

Ключевые слова:

boronic acids, dihydrocoumarins, 1, 4-addition, enantioselective synthesis

Аннотация

Several synthetic approaches are known for the preparation of chiral 4-aryl-3,4-dihydrocoumarins (DHCs). This article considers recently discovered methods for the synthesis of chiral DHCs: enantio­selective Rh(I)-catalyzed 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds, asymmetric reduction of coumarins, oxidation of chiral indanones, hydroesterification of alkenylphenols, and the addition of 1,3-dicarbonyl compounds to o-quinone methides.

Биография автора

Zigmars Leitis, Latvian Institute of Organic Synthesis

Research assistant.

Опубликован

2016-08-11

Выпуск

Раздел

Гетероциклы в фокусе