ASYMMETRIC REACTIONS EMPLOYING 1,3-DIPOLES

Авторы

  • Albert Padwa Department of Chemistry Emory University
  • Scott Bur

DOI:

https://doi.org/10.1007/3281

Ключевые слова:

azomethine imines, azomethine ylides, carbonyl ylides, diazoalkanes, 1, 3-dipoles, nitrones, asymmetric synthesis, cycloaddition

Аннотация

The preparation of heterocyclic compounds using 1,3-dipolar cycloaddition chemistry is now well recognized in the fields of organic synthesis, drug discovery efforts, polymer chemistry, and materials science. As highlighted in this review, a growing area of interest in organic synthesis involves the enantioselectivity aspects of dipolar cycloaddition chemistry for the preparation of many different classes of natural products. Asymmetric synthesis of natural products using chiral substrates has been elegantly accomplished over the past decade using an assortment of dipole intermediates and represents the focus of this review article.

 

Биография автора

Albert Padwa, Department of Chemistry Emory University

Professor of Chemistry

Опубликован

2016-07-18