SYNTHESIS OF 1,6-DIAMINO-2-IMINO-2,3-DIHYDROPYRIMIDIN-4(1<i>Н</i>)-ONE AND PRELIMINARY STUDY OF ITS TWO- AND THREE-COMPONENT REACTIONS

Авторы

  • Ievgen M. Zviagin State Scientific Institution ''Institute for Single Crystals'' of NAS of Ukraine, 60 Nauky Ave., Kharkiv 61072
  • Oleksii S. Zhelavskyi V. N. Karazin Kharkiv National University, 4 Svobody Sq., Kharkiv 61022
  • Svetlana V. Shishkina State Scientific Institution ''Institute for Single Crystals'' of NAS of Ukraine, 60 Nauky Ave., Kharkiv 61072
  • Vladimir I. Musatov State Scientific Institution ''Institute for Single Crystals'' of NAS of Ukraine, 60 Nauky Ave., Kharkiv 61072
  • Alexander V. Borisov Enamine Ltd., 23 Alexandra Matrosova St., Kyiv 01103
  • Valentin A. Chebanov НТК "Институт монокристаллов" НАН Украины

DOI:

https://doi.org/10.1007/3711

Ключевые слова:

arylidene pyruvic acids, pyrimidine derivatives, microwave-assisted synthesis, molecular diversity, multicomponent reactions

Аннотация

A new heterocyclic compound, 1,6-diamino-2-imino-2,3-dihydropyrimidin-4(1H)-one, was synthesized for the first time and some of its chemical properties were studied. This pyrimidinone showed very unusual reactivity comparing to analogous compounds in reactions with alkylating and acylating agents and in other two-component reactions. Three-component reactions involving 1,6-diamino-2-imino-2,3-dihydropyrimidin-4(1H)-one were also explored.A new heterocyclic compound – 1,6-diamino-2-imino-2,3-dihydropyrimidin-4(1H)-one – was synthesized for the first time and some of its chemical properties were studied. This pyrimidinone showed very unusual reactivity comparing to analogous compounds in reactions with alkylating and acylating agents and in other two-component reactions. Three-component reactions involving 1,6-diamino-2-imino-2,3-dihydropyrimidin-4(1H)-one were also explored.

 

Загрузки

Опубликован

2017-05-02

Выпуск

Том 53 № 4 (2017): Многокомпонентные реакции в синтезе гетероциклов

Раздел

Оригинальные статьи