[3+2] CYCLOADDITION-BASED ONE-POT SYNTHESIS OF 3,9-DIAZABICYCLO[4.2.1]NONANE-CONTAINING SCAFFOLD

Авторы

  • Xiaofeng Zhang Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston MA 02125
  • Marc Legris Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston MA 02125
  • Alex M. Muthengi Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston MA 02125
  • Wei Zhang Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston MA 02125

DOI:

https://doi.org/10.1007/3722

Ключевые слова:

3, 9-diazabicyclo[4.2.1]nonane, [3 2] cycloaddition, 1, 3-dipolar cycloaddition, multicomponent reaction, one-pot synthesis

Аннотация

Three-component [3+2] cycloaddition followed by reduction and lactamization has been developed as a one-pot methodology for diastereoselective synthesis of 3,9-diazabicyclo[4.2.1]nonane-containing scaffold.

Биография автора

Wei Zhang, Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston MA 02125

Professor and Director of the Center for Green Chemistry

Опубликован

2017-05-09