ACIDIC IONIC LIQUIDS: HIGHLY EFFICIENT CATALYSTS FOR ONE-POT FOUR-COMPONENT SYNTHESIS OF PYRAZOLO[1,2-<i>b</i>]PHTHALAZINES UNDER SOLVENT-FREE CONDITIONS

Авторы

  • Behjat Pouramiri Department of Chemistry, Shahid Bahonar University of Kerman, Kerman 76169
  • Reza Ghahramani Far Department of Chemistry, Islamic Azad University of Kerman, Kerman 7635131167
  • Mahboobeh Zahedifar Department of Chemistry, Faculty of Science, University of Jiroft, Jiroft 7867161167

DOI:

https://doi.org/10.1007/4346

Ключевые слова:

pyrazolo[1, 2-b]phthalazines, ionic liquid, multicomponent reactions, solvent-free

Аннотация

A series of novel pyrazolo[1,2-b]phthalazine-2-carboxylate derivatives has been synthesized via one-pot four-component reaction of aromatic aldehyde, ethyl or methyl acetoacetate, hydrazine hydrate, and phthalic anhydride in the presence of acidic ionic liquids such as 3-methyl-1-sulfo-1H-imidazol-3-ium chloride, 1,3-disulfo-1H-imidazol-3-ium chloride, and triethyl(sulfo)ammonium chloride as the catalyst. This method involves particular advantages such as environmentally benign catalysts, high yields of product, reusability of ionic liquids with high activity, short reaction times, no hazardous solvent, and easy workup.

Загрузки

Опубликован

2018-12-12

Выпуск

Том 54 № 11 (2018)

Раздел

Оригинальные статьи