RECENT PROGRESS IN THE SYNTHESIS OF MORPHOLINES

Авторы

  • Vitalii A. Palchykov Oles Honchar Dnipro National University
  • Valentyn A. Chebanov SSI “Institute for Single Crystals” NAS of Ukraine,

DOI:

https://doi.org/10.1007/4834

Ключевые слова:

1, 2-amino alcohols, aziridines, epoxides, morpholines, 4-oxazinanes.

Аннотация

The morpholine (1,4-oxazinane) motif attracted significant attention due to its widespread availability in natural products and biologically relevant compounds. This review describes recent advances in the synthesis of morpholines and their carbonyl-containing analogs from 1,2amino alcohols, aziridines, epoxides, and related compounds. Special attention is paid to the syntheses performed in a stereoselective manner and using transition metal catalysis. Selected works published since 2013 are covered.

 

Опубликован

2019-05-22