SYNTHESIS AND BIOLOGICAL ACTIVITIES OF 4<i>H</i>-3,1-BENZOTHIAZIN-4-ONES

Авторы

  • Lan Phuong Vu Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, Bonn 53121
  • Michael Gütschow Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, Bonn 53121

DOI:

https://doi.org/10.1007/5741

Ключевые слова:

4H-3, 1-benzothiazin-4-ones, enzyme inhibitors, receptors antagonists, ring closure

Аннотация

4H-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4H-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.

Загрузки

Опубликован

2020-07-10

Выпуск

Том 56 № 6 (2020): Гетероциклические соединения в медицинской химии

Раздел

Обзорные статьи