GROUP-ASSISTED PURIFICATION CHEMISTRY PRINCIPLES TO ACCESS HIGHLY SUBSTITUTED ZWITTERIONIC FURANS <i>via</i> FAST, CONCISE, AND EFFICIENT ONE-POT THREE-COMPONENT ASSEMBLY

Авторы

  • Abdolali Alizadeh Department of Chemistry, Tarbiat Modares University, P. O. Box 14115-175, Tehran, Iran
  • Reza Rezaiyehraad Department of Chemistry, Tarbiat Modares University, P. O. Box 14115-175, Tehran, Iran

DOI:

https://doi.org/10.1007/5918

Ключевые слова:

3-cyanochromones, dialkyl acetylenedicarboxylate, triphenylphosphine, zwitterionic furans, one-pot reaction, three-component reaction.

Аннотация

Novel highly substituted zwitterionic furans were generated through the in situ formation of phosphonium salts. Firstly, intermediate salts were obtained via nucleophilic attack of Huisgen zwitterion to 3-cyanochromones. Finally, these intermediate salts underwent a proton migration, intramolecular cyclization, and ring-opening reaction to convert to the target products. The synthesized furans could be easily purified without traditional purification techniques (chromatography and recrystallization).

Биография автора

Abdolali Alizadeh, Department of Chemistry, Tarbiat Modares University, P. O. Box 14115-175, Tehran, Iran

abdol_alizad@yahoo.com

Загрузки

Опубликован

2021-03-15

Выпуск

Том 57 № 3 (2021)

Раздел

Оригинальные статьи