ADDITION REACTION OF VARIOUS AZOLES TO PERFLUOROMETHYL VINYL ETHER

Авторы

  • Kirill I. Petko Институт органической химии НАН Украины
  • Andrey A. Filatov Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02660, Ukraine Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine

DOI:

https://doi.org/10.1007/6253

Ключевые слова:

azoles, perfluoromethylvinyl ether, addition reaction, lipophilicity.

Аннотация

The addition reaction of perfluoromethyl vinyl ether to various azoles – derivatives of pyrrole, imidazole, pyrazole, indole, benzotriazole, carbazole, and triazole has been demonstrated. The reaction conditions depended both on melting point and nucleophilicity of the heterocycle. The obtained products are hydrolytically and thermally stable, have highly lipophilic moiety and can serve as useful precursors in different synthesis of bioactive compounds.

Биографии авторов

Kirill I. Petko, Институт органической химии НАН Украины

отдел №8 старшинй научный сотрудник, кандидат химических наук.

Andrey A. Filatov, Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv 02660, Ukraine Enamine Ltd., 78 Chervonotkatska St., Kyiv 02094, Ukraine

Отдел химии фтора. Младший научный сотрудник. Координатор поставок реактивов фирмы Енамин

Загрузки

Опубликован

2021-06-19

Выпуск

Том 57 № 6 (2021)

Раздел

Оригинальные статьи