A NOVEL AND SIMPLE SYNTHESIS OF ETHERS OF HYDROXYPYRIDINES WITH HEXAFLUOROPROPAN-2-OL <i>VIA</i> DIAZOTIZATION OF AMINOPYRIDINES AND AMINOQUINOLINES UNDER ACID-FREE CONDITIONS

Авторы

  • Victor D. Filimonov Национальный исследовательский Томский политехнический университет
  • Aldar N. Sanzhiev The Kizhner Research Center, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia
  • Roman O. Gulyaev The Kizhner Research Center, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia
  • Elena A. Krasnokutskaya The Kizhner Research Center, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia
  • Alexander A. Bondarev Department of Biomedicine, Altai State University, 61 Lenina Ave., Barnaul 656049, Russia

DOI:

https://doi.org/10.1007/6851

Ключевые слова:

aminopyridines, aminoquinolines, anilines, ethers, 1, 3, 3-hexafluoropropan-2-ol, diazotization.

Аннотация

Herein, we report the first example of diazotization of aminopyridines and aminoquinolines with t-BuONO in hexafluoropropan-2-ol in the absence of acids or other initiators. For aminopyridines, this reaction is the first general route toward 2-, 3-, and 4-[(1,1,1,3,3,3-hexafluoropropan-2-yl)oxy]pyridines.

Биографии авторов

Victor D. Filimonov, Национальный исследовательский Томский политехнический университет

Институт физики высоких технологий, заведующий кафедрой биотехнологии и органической химии (БИОХ)

Aldar N. Sanzhiev, The Kizhner Research Center, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia

The Kizhner Research Center, assistant

Roman O. Gulyaev, The Kizhner Research Center, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia

The Kizhner Research Center, PhD student

Elena A. Krasnokutskaya, The Kizhner Research Center, National Research Tomsk Polytechnic University, 30 Lenina Ave., Tomsk 634050, Russia

The Kizhner Research Center, director

Alexander A. Bondarev, Department of Biomedicine, Altai State University, 61 Lenina Ave., Barnaul 656049, Russia

Department of Biomedicine, researcher

Загрузки

Опубликован

2022-12-20

Выпуск

Том 58 № 12 (2022)

Раздел

Оригинальные статьи