A SIMPLE ROUTE FOR THE SYNTHESIS OF SUBSTITUTED THIAZOLE DERIVATIVES BY MULTICOMPONENT REACTION BETWEEN ARYLGLYOXALS, ACETYLACETONE OR ETHYL ACETOACETATE, AND THIOSEMICARBAZONES
DOI:
https://doi.org/10.1007/7255Ключевые слова:
acetylacetone, arylglyoxals, ethyl acetoacetate, thiazole, multicomponent reaction.Аннотация
An effective one-pot three-component protocol for the synthesis of polysubstituted thiazole derivatives is reported. The reaction proceeds between arylglyoxals, thiosemicarbazones, and acetylacetone or ethyl acetoacetate in ethanol as solvent and in the presence of acetic acid as catalyst.
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Опубликован
2023-11-01
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Оригинальные статьи