MICROWAVE-PROMOTED AUTOMATED SYNTHESIS OF COUMARIN LIBRARY

Авторы

  • M. Katkevičs Latvian Institute of Organic Synthesis, Riga LV 1006
  • A. Kontijevskis Latvian Institute of Organic Synthesis, Riga LV 1006
  • I. Mutule Latvian Institute of Organic Synthesis, Riga LV 1006
  • E. Sūna Latvian Institute of Organic Synthesis, Riga LV 1006

DOI:

https://doi.org/10.1007/7670

Ключевые слова:

coumarin, microwave promoted synthesis, library synthesis

Аннотация

A 30-membered library of coumarins has been synthesized in a microwave assisted Pechmann reaction using neat trifluoroacetic acid both as an acidic reagent and a reaction media. Alternatively, polymer-supported sulfonic acid Amberlyst-15 could also be employed to facilitate the formation of coumarins. The use of purpose-built microwave synthesizer with liquid handling tools rendered automated synthesis of coumarin library feasible.

How to Cite
Katkevičs, M.; Kontijevskis, A.; Mutule, I.; Sūna, E.  Chem. Heterocycl. Compd. 2007, 43, 151. [Khim. Geterotsikl. Soedin. 2007, 200.]

For this article in the English edition see DOI 10.1007/s10593-007-0025-x

Загрузки

Опубликован

2023-04-03

Выпуск

№ 2 (2007)

Раздел

Оригинальные статьи