NEW SIMPLE AND ONE-POT SYNTHETIC ROUTES TO POLYFUNCTIONALLY SUBSTITUTED IMIDAZO[1,2-<i>a</i>]PYRIDINES, PYRIDO[1,2-<i>a</i>]PYRIMIDINES, PYRIDO[1,2-<i>a</i>]-1,3-DIAZEPINES, AND IMIDAZO[1,2-<i>a</i>]PYRIMIDINES
DOI:
https://doi.org/10.1007/8118Ключевые слова:
arylidenemalononitriles, nitroenamines, Mannich reactionАннотация
Reactions of arylidenemalononitriles with 2-nitromethylene-substituted imidazolidine, hexahydropyrimidine and hexahydro-1,3-diazepine afforded the title derivatives. Reaction of 2-nitromethylenehexahydropyrimidine with benzylamine or n-butylamine and formalin in a molar ratio of 1:1:2 gave the hexahydro-1H-imidazo[1,2-c]pyrimidine derivatives. Treatment of 2-nitro- methyleneimidazolidine and hexahydropyrimidine with secondary aliphatic amines and formalin in a molar ratio of 1:1:1 afforded corresponding methylene bis-compounds.
How to Cite
Hammouda, M.; Abou Zeid, Z. M.; Metwally, M. A. Chem. Heterocycl. Compd. 2005, 41, 1525. [Khim. Geterotsikl. Soedin. 2005, 1850.]
For this article in the English edition, see DOI 10.1007/s10593-006-0031-4