REACTIONS OF 6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE WITH <i>o</i>-QUINONE METHIDES
DOI:
https://doi.org/10.1007/1485Keywords:
o-hydroxybenzyl alcohols, 6, 7-dimethoxy-3, 4-dihydroisoquinoline, Mannich bases, o-quinone methidesAbstract
Products of heterocyclization, 9,10-dimethoxy-12,13-dihydro-7aH,15H-naphtho[1',2':5,6][1,3]oxazino[2,3-a]isoquinolines, were isolated on condensing 6,7-dimethoxy-3,4-dihydroisoquinoline with 1‑dimethylaminomethyl-2-naphthols. In the case of o-hydroxybenzyl alcohols products of a Michael aza reaction, 2-[(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl]phenols were obtained.
Authors: V. A. Osyanin, E. A. Ivleva, D. V. Osipov, and Yu. N. Klimochkin
English Translation in Chemistry of Heterocyclic Compounds, 2011, 47 (7), pp 845-850