INTERACTION OF 3,8-DISUBSTITUTED IMIDAZO[5,1-<i>c</i>][1,2,4]TRIAZINES WITH NUCLEOPHILES

Authors

  • Е. В. Садчикова Ural Federal University named after the First President of Russia B. N. Yeltsin
  • В. С. Мокрушин Ural Federal University named after the First President of Russia B. N. Yeltsin

DOI:

https://doi.org/10.1007/1789

Keywords:

diazepines, imidazolylhydrazones, imidazotriazines, oxazepines, polycondensed heterocyclic systems

Abstract

We studied the reactivity of diethyl 4-aminoimidazo[5,1-с][1,2,4]triazine-3,8-dicarboxylate in reactions with nucleophiles and demonstrated the possibility of selective formation of monoamides by interaction with primary and secondary aliphatic amines. It was determined that the carbon atom at position 4 of imidazo[1,5-с][1,2,4]triazine system underwent nucleophilic attack, enabling the synthesis of imidazo-[1',5':3,4][1,2,4]triazino[5,6-b][1,5]benzoxazepines and imidazo[1',5':3,4][1,2,4]triazino[5,6‑b][1,5]benzodiazepines, as well as (pyrazol-4-ylidenehydrazino)imidazoles, depending on the bisnucleophile used.

How to Cite
Sadchikova, E. V.; Mokrushin, V. S. Chem. Heterocycl. Compd. 2014, 50, 1014. [Khim. Geterotsikl. Soedin. 2014, 1100.]

For this article in the English edition see DOI 10.1007/s10593-014-1557-5

Author Biographies

Е. В. Садчикова, Ural Federal University named after the First President of Russia B. N. Yeltsin

Елена Владимировна Садчикова

доцент кафедры технологии органического синтеза ХТИ УрФУ

В. С. Мокрушин, Ural Federal University named after the First President of Russia B. N. Yeltsin

Владимир Степанович Мокрушин

профессор кафедры технологии органического синтеза ХТИ УрФУ

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Published

2014-08-01

Issue

No. 7 (2014)

Section

Original Papers