A NEW FACILE METHOD FOR THE SYNTHESIS OF 3-IMIDAZOLYLPROPIONIC ACID <i>N</i>-OXIDES

Authors

  • Anton V. Kutasevich D. Mendeleyev University of Chemical Technology of Russia
  • Valery P. Perevalov D. Mendeleyev University of Chemical Technology of Russia
  • Vitaly S. Mityanov D. Mendeleyev University of Chemical Technology of Russia
  • Boris V. Lichitsky N.D. Zelinsky Institute of Organic Chemistry
  • Andrey N. Komogortsev N.D. Zelinsky Institute of Organic Chemistry
  • Mikhail M. Krayushkin N.D. Zelinsky Institute of Organic Chemistry
  • Tatyana Yu. Koldaeva D. Mendeleyev University of Chemical Technology of Russia
  • Vladimir S. Miroshnikov D. Mendeleyev University of Chemical Technology of Russia

DOI:

https://doi.org/10.1007/4905

Keywords:

Russian Foundation for Basic Research

Abstract

A facile and efficient method for the preparation of 3-imidazolylpropionic acids N-oxides has been developed. It consists in the condensation of 2-unsubstituted imidazole N-oxide with aldehyde and Meldrum’s acid with the following hydrolysis of corresponding adduct. This method permits a broad variation in the structure of starting aldehydes as well as N-oxides.

Downloads

Published

2019-03-12

Issue

Vol. 55 No. 2 (2019)

Section

Original Papers